David Foster Wallace praised the book in interviews and listed it first on his list of top ten favorite books.
In an October 2013 interview in New York magazine, U.S. Supreme Court Justice Antonin Scalia, professed his admiration for the book. Scalia remarked, "The Screwtape Letters is a great book. It really is, just as a study of human nature." The book was discussed in the highly publicized interview during Scalia's discourse regarding the nature of his Catholic faith.