Dmitri Shostakovich's opera The Nose, first performed in 1930, is based on this story. A short film based on the story was made by Alexandre Alexeieff and Claire Parker in 1963 and used pinscreen animation.
A play for radio based on the story was written by UK author Avanti Kumar and first produced and broadcast in Ireland by RTÉ in 1995.
In April 2002, the BBC Radio 4 comedy series Three Ivans, Two Aunts and an Overcoat broadcast an adaptation of the story starring Stephen Moore.
An album in Romanian, Nasul, based on the story was released by Ada Milea and Bogdan Burlăcianu in 2007.
A play based on the short story was written by Tom Swift and produced by The Performance Corporation in 2008.
The Fat Git Theatre Company performed their adaptation of the short story in 2011.
WMSE (91.7 FM in Milwaukee, WI) broadcast an adaptation by Wisconsin Hybrid Theater (Radio WHT)in 2011.
The Moscow Museum of Erotic Art put on an adaptation based on Vladimir Putin losing his genitalia to coincide with the 2012 presidential election.