Four years after its publication, The Kite Runner was adapted as a motion picture starring Khalid Abdalla as Amir, Homayoun Ershadi as Baba, and Ahmad Khan Mahmoodzada as Hassan. It was initially scheduled to premiere in November 2007, but the release date was pushed back six weeks to evacuate the Afghan child stars from the country after they received death threats. Directed by Marc Forster and with a screenplay by David Benioff, the movie won numerous awards and was nominated for an Academy Award, the BAFTA Film Award, and the Critics Choice Award in 2008. While reviews were generally positive, with Entertainment Weekly deeming the final product "pretty good", the depiction of ethnic tensions and the controversial rape scene drew outrage in Afghanistan. Hangama Anwari, the child rights commissioner for the Afghanistan Independent Human Rights Commission, commented, "They should not play around with the lives and security of people. The Hazara people will take it as an insult."
Hosseini was surprised by the extent of the controversy caused by the rape scene and vocalized that Afghan actors would not have been cast had studios known that their lives would be threatened. He believed that the scene was necessary to "maintain the integrity" of the story, as a physical assault by itself would not have affected the audience as much.
The novel was first adapted to the stage in March 2007 by Bay Area playwright Matthew Spangler where it was performed at San Jose State University. Two years later, David Ira Goldstein, artistic director of Arizona Theater Company, organized for it to be performed at San Jose Repertory Theatre. The play was produced at Arizona Theatre Company in 2009, Actor's Theatre of Louisville and Cleveland Play House in 2010, and The New Repertory Theatre of Watertown, Massachusetts in 2012. The theatre adaption premiered in Canada as a co-production between Theatre Calgary and the Citadel Theatre in January 2013. In April 2013, the play premiered in Europe at the Nottingham Playhouse, with Ben Turner acting in the lead role.
Hosseini was approached by Piemme, his Italian publisher, about converting The Kite Runner to a graphic novel in 2011. Having been "a fan of comic books since childhood", he was open to the idea, believing that The Kite Runner was a good candidate to be presented in a visual format. Fabio Celoni provided the illustrations for the project and regularly updated Hosseini on his progress before its release in September of that year. The latter was pleased with the final product and said, "I believe Fabio Celoni's work vividly brings to life not only the mountains, the bazaars, the city of Kabul and its kite-dotted skies, but also the many struggles, conflicts, and emotional highs and lows of Amir's journey."