The Hot Zone

Describe the characteristics of the four levels of BSL.

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Biosafety 1

This level is used for biological agents that do not typically cause disease in adult humans and present minimal danger to laboratory personnel

Biosafety 2

the level of containment precautions necessary to isolate agents of moderate danger to humans

Biosafety 3

the level of containment precautions necessary to isolate agents that can cause serious and fatal disease in humans for which treatments exist. Examples include West Nile virus, rabies, and yellow fever.

Biosafety 4

the level of containment precautions necessary to isolate agents that can cause severe and fatal disease in humans for which treatments do not exist. Examples include Ebola virus, Marburg virus, and smallpox.

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