Who are the three most significant women in Gilgamesh. what roles do these women play to show their significance?

Shamhat

A temple prostitute sent by Gilgamesh to civilize Enkidu. Shamhat seduces Enkidu and he sleeps with her for six days and seven nights. She brings him back to Uruk with her where he first encounters Gilgamesh.

Ninsun

Gilgamesh's mother and a goddess. She prays for Gilgamesh and Enkidu before they embark to fight Humbaba in the cedar forest.

Ishtar/Irnini

Goddess of Love, Fertility, and War, and daughter of Anu. Ishtar sends the Bull of Heaven to attack Gilgamesh after he spurns her advances.

Siduri

A barmaid and alewife that Gilgamesh encounters on his journey into the Underworld. Siduri resides in a cottage by the sea. She discourages Gilgamesh on his pursuit for immortality but ultimately directs him to the boatman Urshanabi.