Lehninger Principles of Biochemistry 6th Edition

Published by W.H. Freeman
ISBN 10: 1-42923-414-8
ISBN 13: 978-1-42923-414-6

Chapter 5 - Protein Function - Problems - Page 185: 10

Answer

The antibody binding site (i.e., the epitope of G-actin may not be accessible to antibody when it becomes F-actin)

Work Step by Step

G-actin is a monomer and F-actin is a polymer. The epitope, which was accessible to antibody when it is in G-actin form, may become buried inside the polymer in F-actin form.
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