Lehninger Principles of Biochemistry 6th Edition

Published by W.H. Freeman
ISBN 10: 1-42923-414-8
ISBN 13: 978-1-42923-414-6

Chapter 22 - Biosynthesis of Amino Acids, Nucleotides, and Related Molecules - Problems - Page 927: 5

Answer

Tyrosine is normally a nonessential amino acid, but individuals with a genetic defect in phenylalanine hydroxylase require tyrosine in their diet for normal growth.

Work Step by Step

If $phenylalanine$ hydroxylase is defective, the biosynthetic route to tyrosine is blocked and tyrosine must be obtained from the diet.
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