Essential Cell Biology, 4th Edition

Published by Garland Science
ISBN 10: 0815344546
ISBN 13: 978-0-81534-454-4

Chapter 20 - Cell Communities: Tissues, Stem Cells, and Cancer - Questions - Page 688: Question 20-2 A

Answer

Yes, the collagen mutation would be detrimental even if it was only one of the copies was defective.

Work Step by Step

Three collagen chains are required to form the triple helix. As such, if even one collagen molecule is defective, it will hinder the entire assembly. Collagen mutations are dominant and have a deleterious effect even if there is a normal copy of the gene.
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