Essential Cell Biology, 4th Edition

Published by Garland Science
ISBN 10: 0815344546
ISBN 13: 978-0-81534-454-4

Chapter 10 - Modern Recombinant DNA Technology - Questions - Page 335: Question 10-3

Answer

This statement is false. It's true that the cDNA will "tell" the protein sequence, but the sequence of a protein alone cannot tell its shape. Protein shape/conformation is something that has to be experimentally determined, and this is important because conformation is the source of interaction and function. We will have some idea of conformation based on the sequence (certain motifs can be given away & hydrophobic residues tend to end up in the structural interior).

Work Step by Step

This statement is false. It's true that the cDNA will "tell" the protein sequence, but the sequence of a protein alone cannot tell its shape. Protein shape/conformation is something that has to be experimentally determined, and this is important because conformation is the source of interaction and function. We will have some idea of conformation based on the sequence (certain motifs can be given away & hydrophobic residues tend to end up in the structural interior).
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