Answer
B.
Work Step by Step
By definition, intracellular receptors binds to hydrophobic molecules and then alter gene expression by binding to DNA (B.). A. refers to what any receptor does, and so is too vague to be true, and C. refers to what membrane-bound receptors do, not intracellular receptors. D. is wrong because receptor proteins cannot serve as second messengers (those are things like Ca2+ ions).