For a large cell, one would need to create a complex organization, since small cells like those of prokaryotes are simple in organization.
Work Step by Step
Think of cells as analogous with cities. Larger cities have complex structures (many different intersecting roads, coliseums, museums, etc.) compared to small towns which might one or two streets and a single store. In the same way, for a cell to become very large, it would need to have complex organization.