Answer
We see that the filtrate turns hpertonic and it is impermeable to H2O. Na and Cl are pumped in interstitial fluid and causes a decrease of solute concentration within the tubule. The interstitial fluid located at the tip of the loop of Henle and the very deep portions of the medullla are hypertonic because of 2 things. First the loop of henle is a conutercurrent multiplier and creates a osmotic gradient. second is the vasa recta is a countercurrent exchanger that keeps the osmotic gradient by being a passive exchange mechanism that functions to dispose of water in the medullary areas but in turns leave salt behind. at the tip of Henle, the filtrate is hypertonic because of passive diffusion of H20 water.
Work Step by Step
We see that the filtrate turns hpertonic and it is impermeable to H2O. Na and Cl are pumped in interstitial fluid and causes a decrease of solute concentration within the tubule. The interstitial fluid located at the tip of the loop of Henle and the very deep portions of the medullla are hypertonic because of 2 things. First the loop of henle is a conutercurrent multiplier and creates a osmotic gradient. second is the vasa recta is a countercurrent exchanger that keeps the osmotic gradient by being a passive exchange mechanism that functions to dispose of water in the medullary areas but in turns leave salt behind. at the tip of Henle, the filtrate is hypertonic because of passive diffusion of H20 water.
