Anatomy & Physiology: The Unity of Form and Function, 7th Edition

Published by McGraw-Hill Education
ISBN 10: 0073403717
ISBN 13: 978-0-07340-371-7

Chapter 3 - Section 3.2 - The Cell Surface - Before You Go On - Page 90: 10

Answer

Adenylate cyclase, cAMP, and kinases are all molecules involved in the transduction of cellular signals that occur with the activation of a G-protein receptor. Each of these contribute to the function of the cell by triggering physiological changes within it, and allowing for communication both intracellularly and extracellularly.

Work Step by Step

G-protein receptors are peripheral proteins activated by first messenger molecules such as epinephrine, that require a series of physiological changes to happen in order to send a message to a specific part of the body. When G-proteins are activated, they relay the information received to another membrane protein known as adenylate cyclase. This protein removes two phosphate heads from ATP and converts it into a second messenger molecule called cyclic AMP (cAMP). Cyclic AMP activates enzymes known as kinases located in the cytosol of the cell, which later add phosphate groups to other enzymes creating a large-scale intracellular response. Without these important steps, cells wouldn't be able to fully communicate with each other, or even send signals within themselves.
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