Anatomy & Physiology: The Unity of Form and Function, 7th Edition

Published by McGraw-Hill Education
ISBN 10: 0073403717
ISBN 13: 978-0-07340-371-7

Chapter 18 - Section 18.5 - Platelets and Hemostasis-The Control of Bleeding - Before You Go On - Page 703: 26

Answer

A common source of pulmonary embolism is deep vein thrombosis (DVT). Deep vein thrombosis occurs when a blood clot, known as a thrombus, forms in a deep vein, typically in the legs or pelvis. This can occur due to various factors that promote blood clotting, such as prolonged immobility, surgery, trauma, pregnancy, certain medical conditions, and genetic predisposition. The effect of a pulmonary embolism is the obstruction of one of the pulmonary arteries or its branches by a clot that has traveled from a distant site, often a deep vein in the legs. When a clot becomes dislodged from its original location and travels through the bloodstream to the lungs, it can get stuck in a narrower pulmonary artery, causing a blockage. This blockage prevents blood flow to parts of the lung tissue served by the affected artery. The consequences of a pulmonary embolism can range from mild to life-threatening, depending on the size of the clot, the location of the obstruction, and the individual's overall health. Small emboli may not cause noticeable symptoms, or they may lead to mild symptoms like shortness of breath or chest pain. Larger or multiple emboli can have more severe effects, including: 1. **Difficulty Breathing:** Pulmonary emboli can obstruct blood flow to a significant portion of the lung, impairing oxygen exchange and causing shortness of breath, rapid breathing, and even hypoxia (low oxygen levels in the blood). 2. **Chest Pain:** Pulmonary embolism can cause sharp chest pain, often worsened by deep breathing or coughing. This pain might be mistaken for a heart attack. 3. **Cough and Hemoptysis:** Coughing, sometimes accompanied by bloody sputum (hemoptysis), can occur due to the irritation of lung tissue caused by the presence of the clot. 4. **Rapid Heart Rate:** The heart might need to work harder to compensate for the decreased blood flow to the lungs, leading to an elevated heart rate. 5. **Low Blood Pressure:** In severe cases, a large pulmonary embolism can cause a drop in blood pressure due to reduced blood flow to the lungs, leading to shock. 6. **Syncope (Fainting):** In cases of significant pulmonary embolism, reduced oxygen levels in the blood can lead to dizziness and even loss of consciousness. Prompt medical attention is crucial in the case of suspected pulmonary embolism. Diagnosis typically involves imaging tests such as computed tomography pulmonary angiography (CTPA) or ventilation-perfusion (V/Q) scans to visualize the blood flow and identify any blockages. Treatment may include anticoagulant medications to prevent further clot formation and, in some cases, interventions like thrombolytic therapy (clot-dissolving drugs) or surgical procedures to remove or break up the clot. Pulmonary embolism is a serious condition that requires immediate medical intervention to prevent complications and preserve lung function.

Work Step by Step

A common source of pulmonary embolism is deep vein thrombosis (DVT). Deep vein thrombosis occurs when a blood clot, known as a thrombus, forms in a deep vein, typically in the legs or pelvis. This can occur due to various factors that promote blood clotting, such as prolonged immobility, surgery, trauma, pregnancy, certain medical conditions, and genetic predisposition. The effect of a pulmonary embolism is the obstruction of one of the pulmonary arteries or its branches by a clot that has traveled from a distant site, often a deep vein in the legs. When a clot becomes dislodged from its original location and travels through the bloodstream to the lungs, it can get stuck in a narrower pulmonary artery, causing a blockage. This blockage prevents blood flow to parts of the lung tissue served by the affected artery. The consequences of a pulmonary embolism can range from mild to life-threatening, depending on the size of the clot, the location of the obstruction, and the individual's overall health. Small emboli may not cause noticeable symptoms, or they may lead to mild symptoms like shortness of breath or chest pain. Larger or multiple emboli can have more severe effects, including: 1. **Difficulty Breathing:** Pulmonary emboli can obstruct blood flow to a significant portion of the lung, impairing oxygen exchange and causing shortness of breath, rapid breathing, and even hypoxia (low oxygen levels in the blood). 2. **Chest Pain:** Pulmonary embolism can cause sharp chest pain, often worsened by deep breathing or coughing. This pain might be mistaken for a heart attack. 3. **Cough and Hemoptysis:** Coughing, sometimes accompanied by bloody sputum (hemoptysis), can occur due to the irritation of lung tissue caused by the presence of the clot. 4. **Rapid Heart Rate:** The heart might need to work harder to compensate for the decreased blood flow to the lungs, leading to an elevated heart rate. 5. **Low Blood Pressure:** In severe cases, a large pulmonary embolism can cause a drop in blood pressure due to reduced blood flow to the lungs, leading to shock. 6. **Syncope (Fainting):** In cases of significant pulmonary embolism, reduced oxygen levels in the blood can lead to dizziness and even loss of consciousness. Prompt medical attention is crucial in the case of suspected pulmonary embolism. Diagnosis typically involves imaging tests such as computed tomography pulmonary angiography (CTPA) or ventilation-perfusion (V/Q) scans to visualize the blood flow and identify any blockages. Treatment may include anticoagulant medications to prevent further clot formation and, in some cases, interventions like thrombolytic therapy (clot-dissolving drugs) or surgical procedures to remove or break up the clot. Pulmonary embolism is a serious condition that requires immediate medical intervention to prevent complications and preserve lung function.
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