Anatomy & Physiology: The Unity of Form and Function, 7th Edition

Published by McGraw-Hill Education
ISBN 10: 0073403717
ISBN 13: 978-0-07340-371-7

Chapter 18 - Section 18.3 - Blood Types - Before You Go On - Page 689: 14

Answer

The ABO blood group system is determined by the presence or absence of two antigens, A and B, on the surface of red blood cells, as well as the presence or absence of antibodies against the antigens that an individual lacks. Here's a breakdown of the antibodies and antigens present in each of the four ABO blood types: 1. **Blood Type A:** - Antigens on Red Blood Cells: A antigens (A antigen) - Antibodies in Plasma: Anti-B antibodies 2. **Blood Type B:** - Antigens on Red Blood Cells: B antigens (B antigen) - Antibodies in Plasma: Anti-A antibodies 3. **Blood Type AB:** - Antigens on Red Blood Cells: Both A and B antigens (A and B antigens) - Antibodies in Plasma: Neither anti-A nor anti-B antibodies 4. **Blood Type O:** - Antigens on Red Blood Cells: Neither A nor B antigens (no A or B antigens) - Antibodies in Plasma: Both anti-A and anti-B antibodies To clarify: - Blood type A individuals have A antigens on their red blood cells and naturally produce anti-B antibodies in their plasma. - Blood type B individuals have B antigens on their red blood cells and naturally produce anti-A antibodies in their plasma. - Blood type AB individuals have both A and B antigens on their red blood cells and do not naturally produce significant amounts of anti-A or anti-B antibodies in their plasma. - Blood type O individuals have neither A nor B antigens on their red blood cells and naturally produce both anti-A and anti-B antibodies in their plasma. These antigen-antibody interactions are crucial for determining blood compatibility during transfusions or organ transplantation, as mixing incompatible blood types can lead to potentially life-threatening immune reactions.

Work Step by Step

The ABO blood group system is determined by the presence or absence of two antigens, A and B, on the surface of red blood cells, as well as the presence or absence of antibodies against the antigens that an individual lacks. Here's a breakdown of the antibodies and antigens present in each of the four ABO blood types: 1. **Blood Type A:** - Antigens on Red Blood Cells: A antigens (A antigen) - Antibodies in Plasma: Anti-B antibodies 2. **Blood Type B:** - Antigens on Red Blood Cells: B antigens (B antigen) - Antibodies in Plasma: Anti-A antibodies 3. **Blood Type AB:** - Antigens on Red Blood Cells: Both A and B antigens (A and B antigens) - Antibodies in Plasma: Neither anti-A nor anti-B antibodies 4. **Blood Type O:** - Antigens on Red Blood Cells: Neither A nor B antigens (no A or B antigens) - Antibodies in Plasma: Both anti-A and anti-B antibodies To clarify: - Blood type A individuals have A antigens on their red blood cells and naturally produce anti-B antibodies in their plasma. - Blood type B individuals have B antigens on their red blood cells and naturally produce anti-A antibodies in their plasma. - Blood type AB individuals have both A and B antigens on their red blood cells and do not naturally produce significant amounts of anti-A or anti-B antibodies in their plasma. - Blood type O individuals have neither A nor B antigens on their red blood cells and naturally produce both anti-A and anti-B antibodies in their plasma. These antigen-antibody interactions are crucial for determining blood compatibility during transfusions or organ transplantation, as mixing incompatible blood types can lead to potentially life-threatening immune reactions.
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