Anatomy & Physiology: The Unity of Form and Function, 7th Edition

Published by McGraw-Hill Education
ISBN 10: 0073403717
ISBN 13: 978-0-07340-371-7

Chapter 18 - Section 18.1 - Introduction - Before You Go On - Page 678: 5

Answer

**Hemopoiesis** (also known as hematopoiesis) refers to the process of blood cell formation or the production of new blood cells. This process occurs predominantly in the bone marrow, although certain types of blood cells can also be produced in other tissues, such as the lymph nodes and spleen. **After Birth, the Starting Point for Hemopoiesis**: After birth, the primary cell type that serves as the starting point for all hemopoiesis is the **hematopoietic stem cell** (HSC). Hematopoietic stem cells are multipotent cells that have the unique ability to differentiate into various types of blood cells, including red blood cells (erythrocytes), white blood cells (leukocytes), and platelets (thrombocytes). Hematopoietic stem cells are located in the bone marrow and have the capacity for self-renewal, which means they can divide and produce both identical stem cells and more specialized progenitor cells. These progenitor cells further differentiate into various precursor cells that eventually give rise to the different types of blood cells. The process of hemopoiesis involves a highly regulated series of differentiation steps, with different growth factors and cytokines guiding the development of specific blood cell lineages. The ability of hematopoietic stem cells to continually generate new blood cells is essential for the body's ability to maintain proper immune function, oxygen transport, blood clotting, and overall homeostasis.

Work Step by Step

**Hemopoiesis** (also known as hematopoiesis) refers to the process of blood cell formation or the production of new blood cells. This process occurs predominantly in the bone marrow, although certain types of blood cells can also be produced in other tissues, such as the lymph nodes and spleen. **After Birth, the Starting Point for Hemopoiesis**: After birth, the primary cell type that serves as the starting point for all hemopoiesis is the **hematopoietic stem cell** (HSC). Hematopoietic stem cells are multipotent cells that have the unique ability to differentiate into various types of blood cells, including red blood cells (erythrocytes), white blood cells (leukocytes), and platelets (thrombocytes). Hematopoietic stem cells are located in the bone marrow and have the capacity for self-renewal, which means they can divide and produce both identical stem cells and more specialized progenitor cells. These progenitor cells further differentiate into various precursor cells that eventually give rise to the different types of blood cells. The process of hemopoiesis involves a highly regulated series of differentiation steps, with different growth factors and cytokines guiding the development of specific blood cell lineages. The ability of hematopoietic stem cells to continually generate new blood cells is essential for the body's ability to maintain proper immune function, oxygen transport, blood clotting, and overall homeostasis.
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