Anatomy & Physiology: The Unity of Form and Function, 7th Edition

Published by McGraw-Hill Education
ISBN 10: 0073403717
ISBN 13: 978-0-07340-371-7

Chapter 11 - Section 11.2 - Study Guide - Assess Your Learning Outcomes - Page 432: 8

Answer

Dystrophin is a minor protein found in muscle fibers. It is located in a position between the sarcolemma and the outermost myofilaments of a muscle cell.

Work Step by Step

Function of dystrophin: Dystrophin links actin filaments to a protein under the sarcolemma, then via other molecules to the endomysium that wraps myofibers. When actin filaments move they pull on dystrophin ; this pull is transferred to tendons through extracellular connective tissue. Duchenne and Becker muscular dystrophy are X-linked muscle disorder in which dystrophin is defective. This results in weakness, muscle degeneration, and comparatively early death
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