Anatomy & Physiology: The Unity of Form and Function, 7th Edition

Published by McGraw-Hill Education
ISBN 10: 0073403717
ISBN 13: 978-0-07340-371-7

Chapter 10 - Section 10.3 - Muscles of the Trunk - Apply What You Know - Page 330: 1

Answer

The phrenic nerves play a crucial role in the respiratory system by innervating the diaphragm, the main muscle responsible for breathing. Each phrenic nerve controls the contraction and movement of one half (hemidiaphragm) of the diaphragm. The diaphragm's contraction is essential for inspiration (inhaling), as it increases the volume of the thoracic cavity, lowering the air pressure within the lungs and causing air to be drawn in. If a young thoracic surgery resident accidentally severs the patient's left phrenic nerve during surgery for esophageal cancer, it would have the following effects on the patient's respiration: 1. **Paralysis of the Left Hemidiaphragm:** The most immediate and significant effect would be the paralysis of the left hemidiaphragm. Without the innervation from the left phrenic nerve, the left side of the diaphragm would become functionally inactive. As a result, it would not contract during inhalation, and this would lead to a decrease in the overall effectiveness of diaphragmatic contraction during breathing. 2. **Reduced Lung Expansion:** The diaphragm's ability to contract and move downward during inhalation is essential for expanding the lungs and creating negative pressure within the thoracic cavity. Without the contribution of the left hemidiaphragm, the patient's ability to take deep breaths and expand the left lung would be compromised. This could result in reduced lung ventilation and oxygen exchange. 3. **Increased Work of Breathing:** To compensate for the loss of diaphragmatic function on the left side, the right hemidiaphragm and accessory muscles of respiration may have to work harder to maintain adequate ventilation. This increased effort can lead to muscle fatigue and respiratory distress over time, especially during periods of increased physical activity or respiratory demand. 4. **Impaired Exercise Tolerance:** The patient may experience reduced exercise tolerance due to the compromised respiratory function. The inability to take deep breaths and efficiently oxygenate the body can limit physical activities and cause shortness of breath even during mild exertion. 5. **Potential Long-Term Complications:** In the long term, chronic unilateral phrenic nerve injury may lead to diaphragmatic atrophy and decreased lung function on the affected side. This can result in chronic respiratory symptoms and reduced quality of life. To manage this situation, respiratory therapy and rehabilitation may be necessary to help the patient adapt to the reduced lung function and improve their respiratory capacity. In some cases, surgical interventions or nerve grafts may be considered to restore function to the affected phrenic nerve, but the success of such procedures depends on various factors, including the extent of nerve damage.

Work Step by Step

The phrenic nerves play a crucial role in the respiratory system by innervating the diaphragm, the main muscle responsible for breathing. Each phrenic nerve controls the contraction and movement of one half (hemidiaphragm) of the diaphragm. The diaphragm's contraction is essential for inspiration (inhaling), as it increases the volume of the thoracic cavity, lowering the air pressure within the lungs and causing air to be drawn in. If a young thoracic surgery resident accidentally severs the patient's left phrenic nerve during surgery for esophageal cancer, it would have the following effects on the patient's respiration: 1. **Paralysis of the Left Hemidiaphragm:** The most immediate and significant effect would be the paralysis of the left hemidiaphragm. Without the innervation from the left phrenic nerve, the left side of the diaphragm would become functionally inactive. As a result, it would not contract during inhalation, and this would lead to a decrease in the overall effectiveness of diaphragmatic contraction during breathing. 2. **Reduced Lung Expansion:** The diaphragm's ability to contract and move downward during inhalation is essential for expanding the lungs and creating negative pressure within the thoracic cavity. Without the contribution of the left hemidiaphragm, the patient's ability to take deep breaths and expand the left lung would be compromised. This could result in reduced lung ventilation and oxygen exchange. 3. **Increased Work of Breathing:** To compensate for the loss of diaphragmatic function on the left side, the right hemidiaphragm and accessory muscles of respiration may have to work harder to maintain adequate ventilation. This increased effort can lead to muscle fatigue and respiratory distress over time, especially during periods of increased physical activity or respiratory demand. 4. **Impaired Exercise Tolerance:** The patient may experience reduced exercise tolerance due to the compromised respiratory function. The inability to take deep breaths and efficiently oxygenate the body can limit physical activities and cause shortness of breath even during mild exertion. 5. **Potential Long-Term Complications:** In the long term, chronic unilateral phrenic nerve injury may lead to diaphragmatic atrophy and decreased lung function on the affected side. This can result in chronic respiratory symptoms and reduced quality of life. To manage this situation, respiratory therapy and rehabilitation may be necessary to help the patient adapt to the reduced lung function and improve their respiratory capacity. In some cases, surgical interventions or nerve grafts may be considered to restore function to the affected phrenic nerve, but the success of such procedures depends on various factors, including the extent of nerve damage.
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