Answer
negative
Work Step by Step
see: Signs of the Trigonometric Functions (p.412)
$\left[\begin{array}{lll}
Quadrant & Positive & Negative\\
I & all & none\\
II & sin, csc & cos, sec, tan, cot\\
III & tan, cot & sin, csc, cos, sec\\
IV & cos, sec & sin, csc, tan, cot
\end{array}\right]$
In Q.II,
sine is positive,
cosine is negative
Their product is negative