Answer
-2
Work Step by Step
$\frac{(-4)(-3)-(-2)(-1)}{-10+5}$ $\longrightarrow$ resolve multiplication
=$\frac{12-2}{-10+5}$ $\longrightarrow$ simplify numerator and denominator
=$\frac{10}{-5}$ $\longrightarrow$ divide
=$-2$
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