Answer
$67584x^2$
Work Step by Step
The $r+1$ th term in the binomial expansion of $(x+y)^n$ is:
$\binom{n}{r}x^{n-r}y^r$
Here $y=-2$, $n=12$:
$r+1=11$
$r=10$
The indicated term is:
$\binom{12}{10}x^{12-10}(-2)^{10}=66x^2\times1024=67584x^2$