Answer
$41$
Work Step by Step
Using $(a+b)(a-b)=a^2-b^2$, or the product of the sum and difference of like terms, and using the properties of radicals, the given expression, $
(-4+5i)(-4-5i)
,$ simplifies to
\begin{array}{l}\require{cancel}
(-4)^2-(5i)^2
\\\\=
16-25i^2
\\\\=
16-25(-1)
\\\\=
16+25
\\\\=
41
.\end{array}