An unsold television pilot was filmed by Mirisch Productions in 1961 featuring Vic Damone and Tina Louise. As a favor to the production company, Jack Lemmon and Tony Curtis agreed to film cameo appearances, returning as their original characters, Daphne and Josephine, at the beginning of the pilot. Their appearance sees them in a hospital where Jerry (Lemmon) is being treated for his impacted back tooth and Joe (Curtis) is the same O blood type.
In 1972, a musical play based on the screenplay of the film, entitled Sugar, opened on Broadway, and starred Elaine Joyce, Robert Morse, Tony Roberts and Cyril Ritchard, with book by Peter Stone, lyrics by Bob Merrill, and (all-new) music by Jule Styne. A 1991 stage production of this show in London featured Tommy Steele and retained the film's title. In 2002, the ageing Tony Curtis performed in a stage production of the film, cast as the character originally played by Joe E. Brown (Osgood Fielding III).