- Siddhartha: The protagonist.
- Govinda: A friend and follower of Gotama.
- Siddhartha’s Father: A Brahmin who was unable to satisfy Siddhartha's quest for enlightenment.
- The Samanas: Traveling ascetics who tell Siddhartha that deprivation leads to enlightenment.
- Gotama: A spiritual leader Buddha, whose Teachings are rejected but whose power of self-experience and self-wisdom is completely praised by Siddhartha.
- Kamala: A courtesan and Siddhartha's sensual mentor, mother of his child, Young Siddhartha. Dies of a snake bite while on a pilgrimage, hoping to see the Buddha before she dies, leaving Young Siddhartha with Siddhartha and Vasudeva.
- Kamaswami: A merchant who instructs Siddhartha on business.
- Vasudeva: An enlightened ferryman and spiritual guide of Siddhartha.
- Young Siddhartha: Son of Siddhartha and Kamala. Lives with Siddhartha for a time but runs away.
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