The soundtrack features the songs (among others);
- "Oh, Pretty Woman" by Roy Orbison, which inspired its title
- Roxette's "It Must Have Been Love," originally released in December 1987, reached No. 1 on the Billboard Hot 100 in June 1990
- "King of Wishful Thinking" by Go West
- "Show Me Your Soul" by Red Hot Chili Peppers
- "No Explanation" by Peter Cetera
- "Wild Women Do" by Natalie Cole
- "Fallen" by Lauren Wood
The soundtrack has been certified triple platinum by the Recording Industry Association of America (RIAA).[49]
The opera featured in the film is La Traviata, which also served as inspiration for its plot. The highly dramatic aria fragment that is repeated is the end of "Dammi tu forza!" ("Give me strength!"), from the opera. Roberts sings the song "Kiss" by Prince while she is in the tub and Gere's character is on the phone. Background music is composed by James Newton Howard. The piano piece Gere's character plays in the hotel lobby was composed and performed by Gere. Entitled "He Sleeps/Love Theme," this piano composition is inspired by Bruce Springsteen's "Racing in the Street."
