Act 5 Scene 2
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Basically Othello figures out he's been duped. Othello has killed Desdemona but it is too late for any redemption. Iago has killed his own wife during her valiant defence of the woman she loves (Desdemona). In the final moment of the play, Iago, who has directed action throughout, ends up as a spectator to his own misdeeds.
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Othello tells her that he found her handkerchief with Cassio, though Desdemona insists it must not be true; she pleads with Othello not to kill her right then, but he begins to smother her. Emilia knocks, curious about what is going on; Othello lets her in, but tries to conceal Desdemona, who he thinks is already dead. Emilia brings the news of Roderigo's death, and Cassio's wounding.
Emilia soon finds out that Desdemona is nearly dead, by Othello's hand; Desdemona speaks her last words, and then Emilia pounces on Othello for committing this horrible crime. Othello is not convinced of his folly until Iago confesses his part, and Cassio speaks of the use of the handkerchief; then, Othello is overcome with grief. Iago stabs Emilia for telling all about his plots, and then Emilia dies; the Venetian nobles reveal that Brabantio, Desdemona's father, is dead, and so cannot be grieved by this tragedy now. Othello stabs Iago when he is brought back in; Othello then tells all present to remember him how he is, and kills himself. Cassio becomes temporary leader of the troops at Cyprus, and Lodovico and Gratiano are supposed to carry the news of the tragedy back to Venice. Iago is taken into custody, and his crimes will be judged back in Venice.