The Question and Answer section for Oryx and Crake is a great resource to ask questions, find answers, and discuss the novel.
Crake is working on the immortality project. Jimmy worked in advertising, and Oryx was is charge of making contact lenses, as well as in charge of the marketing for BlyssPluss.
Crake: Watson-Crick Institute, compared with Harvard University, specializes in science/technology (inventions)
Oryx: Martha Graham Academy, specialty performing arts.
The game, Blood and Roses, is a bloody, violent version of Monopoly. Worse, it allowed the player to envision and enact rapes, genocides, and horrific events. It is exactly what the text describes it as.... "It was a wicked game."