what makes the weak characters weak?
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Lennie- mentally weak, he's childlike
Curley- prideful, over compensates for his lack of size by being mean
Candy- physically weak due to the injury of his hand
Curley's wife- no self-esteem
Of Mice and Men
As far as insensitivity, I'd have to say that George can be insensitive to Lennie, but that comes from frustration. Curley is insensitive to his wife's needs and loneliness, thus, she turns it around and looks for attention elsewhere.