How does Steinbeck demonstrate the idea that The Great Depression was a lonely period using the various relationships (or lack thereof) between the characters in the novel?

The Great Depression forced men to be away from families and loved ones. Their transient way of life was isolating and lonely. Although the Great Depression was a factor in their lifestyle, it does not figure prominently in the story. The isolation, however, does. Lennie and George differ from most migrant workers in that they had each other. George felt some isolation as taking care of Lennie was like taking care of a child. George's vision of his dream farm, however, always included Lennie. Their saving grace for living this lifestyle was having each other.

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