- The Chandler novel had been filmed once before, in 1942, as The Falcon Takes Over, directed by Irving Reis, part of a film series which featured George Sanders as The Falcon.
- In 1975, the story was remade under its original title as Farewell, My Lovely starring Robert Mitchum as Marlowe and directed by Dick Richards.
- The film version of Murder, My Sweet was dramatized as an hour-long radio play on June 11, 1945, broadcast of Lux Radio Theater, with Powell and Trevor in their original film roles.[14]
- Another radio adaptation, with Powell and Mike Mazurki reprising their roles, was presented on Hollywood Star Time in 1948, with Mary Astor playing Helen.[2]
- The success of Murder, My Sweet inspired the creation of two radio series: 1947's short-lived Philip Marlow with Van Heflin in the lead role, and The Adventures of Philip Marlowe which played from 1948 to 1951, with Gerald Mohr as Marlowe. The latter was the most popular show on radio in 1949.[2]
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