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Several adaptations have been made of the original Metropolis, including at least two musical theatre adaptations (see Metropolis).
The 2001 animated film Metropolis, is based on an original manga by Osamu Tezuka, which is loosely based on the film, though Tezuka claims he had not seen the film at the time.(see Metropolis).
In December 2007, producer Thomas Schühly (Alexander, The Adventures of Baron Munchausen) gained the remake rights to Metropolis, but it is still unknown if the remake is in production.
Some scenes from the film were featured in the music video for Queen's 1984 hit "Radio Ga Ga".
The 1999 music video for "We're in This Together" by Nine Inch Nails is heavily influenced by the film.
Whitney Houston's music video "Queen of the Night" includes clips from the film as well as Houston wearing a shiny metallic ensemble resembling Maschinenmensch.
Madonna's music video for "Express Yourself" pays homage to the film.
Janelle Monáe based both her concept albums on the original film including her EP, Metropolis: Suite I (The Chase) released mid-2007 and The ArchAndroid released in 2009. The latter also included an homage to Metropolis on the album cover, with the film version of the Tower of Babel among the remainder of the city. The albums follow the adventures of Monáe's alter-ego and robot, Cindi Mayweather, as an messianic figure to the android community of Metropolis.
Australian pop star Kylie Minogue has also paid homage to the film in two of her concert tours, KylieFever2002 and KylieX2008.
A short clip from the film was shown in the music video for System of a Down's "Sugar".
In 2013, the Swedish post-metal band Cult of Luna released an album, Vertikal, based thematically on the film.
In late 2012 and subsequently into early 2013, California based electronic musicians The M Machine released "Metropolis Pt. 1" and "Metropolis Pt. 2", a two part album based on themes and storylines from both the original adaptation and also from the Giorgio Moroder's musical reworking.
The music video for UK punk rock band UFX' 2013 "Crack" remaster uses several sections of the film edited together, including the transformation of the robot into Maria’s double, Freder's nightmarish visions and the robot Maria's dance.