Act two scene two
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Macbeth enters the chambers and tells L Macbeth that he has done the "deed"; He adds that his penance for this will be no sleep,
"Sleep no more!” to all the house;
“Glamis hath murdered sleep, and therefore Cawdor
Shall sleep no more. Macbeth shall sleep no more.”
The pun being on the word sleep, meaning his mind will never be calm again as well as sleep again.
“Glamis hath murdered sleep"
The onomatopoeic "knocking" at the door is actually meant to be heard.
"shriek of the owl" Does an Owl Shriek?
All these literary devices add to the intensity of the play.