How did the relationship between Macbeth and Lady Macbeth change after the murder of the King?

Act II

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In Act II, after the murder of the KIng, Macbeth and his wife totally switch places. He becomes secretive; she becomes unstable. Lady Macbeth is consumed by guilt, whereas, her husband becomes evil. In the end, Lady Macbeth takes her own life; Macbeth is killed in a battle with Macduff.