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Macbeth's guilt and remorse seems to leave him as the play progresses. He and his wife, Lady Macbeth, change places. Where Lady Macbeth pushed and prodded to get the deed done (Claudius' murder), Macbeth initially listened to his conscience..... it would have been so easy not to do as Lady Macbeth wanted. After the murder, Lady Macbeth can't cope with what she been a part of..... she grows evermore upset, paranoid, and emotionally distraught..... the guilt eats her up inside. Macbeth, on the other hand, seems unstoppable and without conscience.... like he lost all sense of morality the moment he killed the King. Macbeth sees himself as invincible and fated to retain his position of power.