define the word regret?identify a comment lady macbeth makes that may regret?

act-3 scene-2 and 3

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Regret: to feel sad, repentant, or disappointed over (something that has happened or been done, especially a loss or missed opportunity).

Here L.Macbeth laments about how getting what you want is not what you expected. She regrets the outcome of their evil deeds.

Naught’s had, all’s spent, Where our desire is got without content. 'Tis safer to be that which we destroy Than by destruction dwell in doubtful joy.