Love in the Time of Cholera

what almost ended Fermina and Dr.Urbino's marriage?

it was after thirty years

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I think this was in part four when Florentino nearly tells Leona about his secret romance with Fermina when Dr. Urbino seeks refuge from a cyclone in Florentino's office.

Source(s)

http://www.gradesaver.com/love-in-the-time-of-cholera/study-guide/section4/