The play was made into a 1962 film, starring Katharine Hepburn as Mary, Ralph Richardson as James, Jason Robards, Jr. as Jamie, Dean Stockwell as Edmund, and Jeanne Barr as Cathleen. The movie was directed by Sidney Lumet. At that year’s Cannes Film Festival Richardson, Robards and Stockwell all received Best Actor awards, and Hepburn was named Best Actress. Hepburn’s performance later drew a nomination for the Academy Award for Best Actress.
In 1973, the ITV Sunday Night Theatre program on British television presented the play intact, starring Laurence Olivier, Constance Cummings, Denis Quilley, and Ronald Pickup, directed by Peter Wood. Olivier won a Best Actor Emmy Award for this performance.
The 1982 made for ABC-TV film, with an all African American cast of Earle Hyman (James), Ruby Dee (Mary), Thommie Blackwell (Jamie), and Peter Francis-James (Edmund).
The 1987 made for TV film starred Kevin Spacey as Jamie, Peter Gallagher as Edmund, Jack Lemmon as James Tyrone, Bethel Leslie as Mary, and Jodie Lynne McClintock as Cathleen. Lemmon was nominated for a Golden Globe for Best Performance by an Actor in Mini-Series or Made-for-TV Movie the following year.
In 1996, another adaptation, directed by Canadian director David Wellington, starred William Hutt as James, Martha Henry as Mary, Peter Donaldson as Jamie, Tom McCamus as Edmund and Martha Burns as Cathleen. The same cast had previously performed the play at Canada's Stratford Festival; Wellington essentially filmed the stage production without significant changes. The film swept the acting awards at the 17th Genie Awards, winning awards for Hutt, Henry, Donaldson and Burns. This version was later aired by PBS on its Great Performances series in 1999.