A television miniseries adaptation, produced by Motown Productions, was broadcast on CBS in 1989. It starred Robert Duvall as Augustus McCrae, Tommy Lee Jones as Woodrow F. Call, Robert Urich as Jake Spoon, Rick Schroder as Newt, Diane Lane as Lorena Wood, Danny Glover as Joshua Deets, and Chris Cooper as July Johnson.
There was also a syndicated spin-off series Lonesome Dove: The Series centering on Newt (Scott Bairstow) taking up residence in the fictional town of Curtis Wells, Montana, having adopted his father's family name of Call. Starting out as a fairly romanticized interpretation of the West, it was heavily revamped for its second season, gaining a much grittier feel and the new title Lonesome Dove: The Outlaw Years. Filming took place in Calgary, Alberta, and a total of 43 episodes were produced, airing between 1994 and 1996.