Act two scene two
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"Cowards die many times before their deaths.
The valiant never taste of death but once.
Of all the wonders that I yet have heard,
It seems to me most strange that men should fear,
Seeing that death, a necessary end,
Will come when it will come."
Caesar's above speech—he's speaking to Calpurnia— alludes to the fact that all men will die, that to worry or fear death is nothing more than foolishness because it can't be avoided. He is also examining that those who are frightened (cowards) die regularly through their fear, whereas a brave man can only die once.
Julius Caesar/ Act II/ Scene II