- 1959: Journey to the Center of the Earth, USA, directed by Henry Levin, starring James Mason and Pat Boone. In the film, the character of Axel becomes Alec and is more adventurous than cowardly as he is in the novel. The film introduces a main antagonist.
- 1978: Viaje al centro de la Tierra, Spain, directed by Juan Piquer Simón, starring Kenneth More and Pep Munné. It was distributed in Great Britain and the US as Where Time Began.
- 2008: Journey to the Center of the Earth is a 3-D film by Eric Brevig. Cast members include Brendan Fraser, Anita Briem and Josh Hutcherson. The film follows as a sequel to the original book.
- 2008: Journey to the Center of the Earth – A direct-to-DVD release by The Asylum, which is a loose adaptation of the original book. It was released as Journey to Middle Earth in the United Kingdom.
Walt Disney Pictures began work on a "Journey" in the late 1990s, but was not happy with the appearance of the subterranean caverns, so the project was scrapped and the cavern scenes were altered and used in the production of their 2001 film Atlantis: The Lost Empire.
- An animated television series, Journey to the Center of the Earth, first broadcast in 1967 on ABC, starring the voices of Ted Knight, Pat Harrington, Jr., and Jane Webb, only loosely based on Verne's novel.
- A limited animation television special in the Famous Classic Tales series was aired by CBS in 1977.
- A 1989 movie called Journey to the Center of the Earth took only the title and a general idea from the Verne novel, and had a unique plot aimed at a teen audience. It was written by Debra Ricci, Regina Davis, Kitty Chalmers, and Rusty Lemorande, and was directed by Lemorande and Albert Pyun. It stars Emo Philips, Paul Carafotes, Jaclyn Bernstein, Kathy Ireland, Janet Du Plessis, Nicola Cowper, Lochner De Kock, and Ilan Mitchell-Smith. It was based on an uncompleted version, more faithful to Verne's text, written and directed by Lemorande, that had been left unfinished because of Cannon Films' premature closure.
- In 1993, NBC aired a made-for-TV film version with a cast including John Neville, F. Murray Abraham and Kim Miyori. The film used the title and general premise of Verne's novel, but had its heroes carry out the journey in an earth-penetrating machine. A television series was supposed to follow, but was never produced.
- The Wishbone 1996 episode "Hot Diggety Dawg" was based on the novel, featuring several major scenes starring the title character as Professor Lidenbrock.
- The 1999 Hallmark Entertainment movie starred Treat Williams, Jeremy London, Bryan Brown, Tushka Bergen, and Hugh Keays-Byrne (this version deviates considerably from Verne's original).
- A TV film version by RHI Entertainment starring Rick Schroder, Peter Fonda, Victoria Pratt, Steven Grayhm and Mike Dopud was shot on location in and around Vancouver on high definition video during the summer of 2007. The show aired on February 4, 2008 and been released on DVD. Victoria Pratt and Peter Fonda's characters were added to the original story.
- A stage version of Journey to the Center of the Earth, written by Gerald Fitzgerald and directed by Steven-Shayle Rhodes, was produced at Pegasus Theatre in Dallas, Texas in 2000, with substantial changes made to the characters and the plot.
- In 2014, Fitzgerald's 2-act script was adapted into a 3-act melodrama format and presented at the Pocket Sandwich Theatre in Dallas, directed by Joey Dietz.
- A thrill ride based on the book, Journey to the Center of the Earth, is open at The Mysterious Island section of Tokyo DisneySea's theme park.
- A water ride at Water World in Federal Heights, Colorado called 'Voyage to the Center of the Earth' is loosely based on the book.
- A mill chute ride, called 'Journey to the Center of the Earth' and loosely based on the book, existed at Dorney Park & Wildwater Kingdom from 1960 to 1992.
- Video games called Journey to the Center of the Earth: in the early 1980s by Ozisoft; in 1988 by Chip Software  for the Commodore 64; in 1989 by Topo Soft  for the ZX Spectrum and in 2003 by Frogwares.
- A board game adaptation of the book designed by Rüdiger Dorn was released by Kosmos in 2008.
- A concept album called Journey to the Centre of the Earth by Rick Wakeman, was released in 1974. It combines song, narration and instrumental pieces to retell the story
- Rick Wakeman released a second concept album called Return to the Centre of the Earth in 1999, it tells the story of a later set of travelers attempting to repeat the original journey.
- An 8-part radio serial was produced for BBC Radio 4 by Howard Jones in 1963. It starred Bernard Horsfall and Jeffrey Banks.
- A radio drama adaptation was broadcast by National Public Radio in 2000 for its series "Radio Tales".
- Alien Voices, an audio theater group led by Leonard Nimoy and John de Lancie, released a dramatized version of Journey to the Center of the Earth through Simon and Schuster Audio in 1997.
- A 90-minute radio adaptation by Stephen Walker directed by Owen O'Callan was first broadcast on BBC Radio 4 Extra on 20 November 2011 and re-broadcast on 11 and 12 November 2012. Nicholas Le Prevost starred as Professor Otto Lidenbrock, Nathaniel Parker as Axel and Oliver Senton as Hans. Rosemary McNab, an original female character who funds and accompanies the expedition (and has affairs with both Hans and Otto along the way), was played by Kristen Millwood.
- Christopher Lloyd's character of Doctor Emmett Brown, one of the two main fictional characters of the Back To The Future film series, attributed the origins of his lifelong devotion to science to having read as a child the works of Jules Verne in general, and Journey to the Centre of the Earth in particular. (This is evident when he reveals that he tried to dig to the Center of the Earth at the age of twelve.) Back to the Future Part III, especially, pays homage to Journey of the Centre of the Earth where Dr. Brown carves his initials in a mineshaft after storing the time machine, just like Arne Saknussemm did to help guide future explorers. At the end of the film, it is also revealed that Dr. Brown's two sons are named Jules and Verne.
- The first part of the second season of Around the World with Willy Fog by Spanish studio BRB Internacional was "Journey to the Centre of the Earth".
- Edgar Rice Burroughs wrote the Pellucidar series using the Journey to the Centre of the Earth concept.
- The surname of Kathy Ireland's character in Alien From L.A. (1988), a film about a girl who falls through the earth and discovers a repressive subterranean society, is Saknussemm.
- The 1992 adventure/role-playing game Quest for Glory III by Sierra Entertainment used Arne Saknoosen the Aardvark as a bit character for exploration information, alluding to the explorer Arne Saknussemm.
- The DC Comics comic book series Warlord took place in Skartaris, a land supposed to exist within a Hollow Earth. Its creator, Mike Grell, has confirmed that "the name comes from the mountain peak Scartaris that points the way to the passage to the earth's core in Journey to the Center of the Earth."
- Louis MacNeice's final play Persons from Porlock contains a reference to Journey to the Centre of the Earth at the beginning. Because his mother used to read it aloud to him, Hank became 'completely fascinated' with 'caves and pot-holes and things' (p 111). At the end of the play 'Herr Professor Lidebrock' is one of the characters Hank meets down the pot hole. Hank says to him, 'Oh, my dear Professor, I've always wanted to meet you, since my mother used to read me your adventures. How you went down the volcano and ran into all those mastodons. But, of course, in your case you got out again.' The Professor replies, 'That was because I am a character in fiction.' He continues, 'Jules Verne invented me'(p 141).
- Halldór Laxness, the only Icelandic author to be awarded the Nobel Prize, situated his novel Under the Glacier in the area of Snæfellsjökull. The glacier has a mystic quality in the story and there are several references to A Journey to the Center of the Earth in connection with it.
- In the Exile computer game series and its remake, the Avernum series, the player's party is exiled to a vast underground cavern similar to the one described in A Journey to the Center of the Earth. It also contains a subterranean ocean and networks of tunnels, but it is lit by bioluminescent mushrooms rather than an electric phenomenon. One of the goals of several of the games is to escape from the cavern.