There are several major themes to the novel. The theme of technology as philosophy describes the belief that everything is possible and that technology allows people to control all aspects of their lives. This view is contradicted throughout the novel by events. Technical breakdowns mark key points in the story (and Walter's life) right up to the upcoming operation that he mentions at the very end, which is thus implied to result in his death.
Faber's dismissal of literature and of anything to do with myths and the arts also plays into the theme of fate versus coincidence, which is preeminent in the plot. Faber is oblivious to the various mythological motifs and twists which bring his story close to a modern tragedy, even as it unfolds in Greece and Rome of all places. Also, the events in Homo Faber are presented in such a way as to seem either a string of coincidences resulting in an unlikely outcome, or a sequence of predestined actions and decisions leading to a necessary outcome. This dichotomy is reflected in a larger series of seeming antinomies: faith or reason, modern knowledge or ancient beliefs, free will or predestination. Walter never resolves this conflict.
The theme of travel plays an important role in the novel. Using many modes of transportation, Walter is constantly on the move, visiting several continents, almost a dozen countries, and dozens of cities, for business and pleasure. This constant travel underscores Walter's sense of dislocation; he has no family, no real home, and no real country. Through travel, Walter is able to avoid permanent connections, to escape responsibilities, and to remain completely unknown and unjudged.
