The exteriors (including the roof scene), and some of the interior shots, of the Gattaca complex were filmed at Frank Lloyd Wright's 1960 Marin County Civic Center in San Rafael, California. The parking lot scenes were shot at the Otis College of Art and Design, distinguished by its punch card-like windows, located near LAX in Los Angeles. The exterior of Vincent Freeman's house was shot at the CLA Building on the campus of California State Polytechnic University, Pomona (Cal Poly Pomona). Other exterior shots were filmed at the bottom of the spillway of the Sepulveda Dam and outside the The Forum in Inglewood. The solar power plant mirrors sequence was filmed at the Kramer Junction Solar Electric Generating Station.
The movie uses a swimming treadmill in the opening minutes to punctuate the swimming and futuristic themes. The futuristic turbine cars are based on 1960s car models like Rover P6, Citroën DS19 and Studebaker Avanti, and futuristic buildings represent modern architecture of the 1950s.