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The Mechanical Hound attacks Montag, and Montag destroys it with the flamethrower, but not before it stabs him with a needle full of anesthetic.
There are two. The original, Montag sets on fire, along with Beatty and the other firemen (I hope you've read the book :)). Then, one is brought in from another city, but Montag escapes that one and it gets blown up along with the city.