Eternal Sunshine of the Spotless Mind was released on DVD in the U.S. in separate anamorphic widescreen and full screen editions on September 28, 2004. Both editions carry English Dolby Digital 5.1 Surround, English DTS 5.1 Surround and French Dolby Digital 5.1 Surround tracks. Bonus features included on this disc are:
- Feature commentary with director Michel Gondry and writer Charlie Kaufman
- Deleted scenes
- A Look Inside Eternal Sunshine of the Spotless Mind
- A Conversation with Jim Carrey and Michel Gondry
- The Polyphonic Spree "Light & Day" music video
- Lacuna, Inc. commercial
A special two-disc widescreen Collector's Edition DVD was released in the U.S. on January 4, 2005. Features on Disc 1 are identical to the single-disc edition. Bonus features on the two-disc edition include:
- Collectible packaging and booklet with photos
- A Conversation with Kate Winslet and Michel Gondry
- Inside the Mind of Michel Gondry
- Additional deleted / extended scenes
- Anatomy of a Scene: Saratoga Avenue
- "The Misadventures of Superdog" by Joel Bar(r)ish (22-second Easter egg accessible just below other features)
A HD DVD edition was released in the U.S. on April 24, 2007, with a 1080p/VC-1 video transfer, and both English and French Dolby Digital Plus 5.1 Surround tracks. This edition includes all the bonus features from the two-disc Collector's Edition, sans the collectible packaging and booklet.
A Blu-ray edition was released in the U.S. on January 25, 2011, with a 1080p/MPEG-4 AVC video transfer, and English DTS-HD Master Audio 5.1 Surround and French DTS 5.1 Surround tracks. This edition also includes all the bonus features from the two-disc Collector's Edition, sans the collectible packaging and booklet.