Provincetown Players (off-Broadway, 1924) – Starring Walter Huston as Ephraim Cabot, Mary Morris as Abbie Putnam and Charles Ellis as Eben Cabot. After two months at the Greenwich Village Theater, this production transferred to Broadway and played an additional nine months, first at the Earl Carroll Theatre, then at George M. Cohan's Theatre and finally at Daly's 63rd Street Theatre, for a total of 420 performances.
Broadway (1952) – Directed by Harold Clurman, produced by The American National Theater and Academy. Starring Karl Malden as Ephraim Cabot, Douglass Watson as Eben Cabot and Carol Stone as Abbie Putnam, 46 performances.
Academy Festival Theatre (Lake Forest, Illinois, 1974) Directed by Vinette Carrol, produced by William T. Gardner. Starring Roscoe Lee Browne as Ephraim Cabot, Glynn Turman as Eben Cabot and Cicely Tyson as Abbie Putnam.
Asmita Theatre (India, 1995) – Directed by Arvind Gaur, translated by Nadira Babbar, starring Deepak Dobriyal, Manu Rishi, Deepak Ochani and Arachana Shintre Joshii, 14 performances.
Goodman Theatre (Chicago, 2009) – Directed by Robert Falls, starring Brian Dennehy as Ephraim Cabot, Carla Gugino as Anna Putnam and Pablo Schreiber as Eben Cabot.
Sri Ram Centre Theatre (Mandi House, New Delhi, India, 2010) – A RAS production. Directed by Deepak Ochaney and Gajraj Nagar, starring Mukul Saran Mathur as Ephraim Cabot, Sanjeela Mathur as Anna Putnam, six performances.
Broadway (2009) – Transfer of the Goodman production; opened April 27, 2009 at the St. James Theater, 32 performances.
New Vic Theatre (Newcastle-under-Lyme, Staffordshire, UK, 2010) – Directed by James Dacre, starring Gareth Thomas as Ephraim Cabot, Victoria Lloyd as Anna Putnam, Cary Crankson as Eben Cabot, Owen Oakeshott as Peter Cabot and Timothy Chipping as Simeon Cabot.
Lyric Hammersmith (2012) – Directed by Sean Holmes and designed by Ian MacNeil, starring Morgan Watkins as Eben Cabot, Denise Gough as Anna Putnam and Finbar Lynch as Ephraim Cabot.
This play was adapted by Balwant Gargi (under the name "Balde Tibbe") in Punjabi, Department of Drama and Dramatics, Jahangirnagar University, Dhaka, Bangladesh, as the second—year final production of 2015. Held on 26 November 2016. Direction: Reza Arif.
Shaw Festival, (2021) - Desire Under the Elms was initially scheduled as a part of the festival's 2020 season, but the season was eventually cancelled due to the COVID-19 pandemic, and the production was moved to the fall of the 2021 season. Directed by Tim Carroll, set by Judith Bowden, Lighting by Kevin Lamotte, costumes by Joyce Padua.
