Long after Thomas Wyatt's death, his only legitimate son, Thomas Wyatt the Younger, led a thwarted rebellion against Henry's daughter, Mary I, for which he was executed. The rebellion's aim was to set the Protestant-minded Elizabeth, the daughter of Anne Boleyn, on the throne. His sister Margaret Wyatt was the mother of Henry Lee of Ditchley, from whom descend the Lees of Virginia, including Robert E. Lee. Wyatt's grandson, Sir George Wyatt, was an ancestor of Wallis, Duchess of Windsor, wife of King Edward VIII, later Duke of Windsor. Thomas Wyatt's great-grandson was Virginia Colony governor Sir Francis Wyatt.
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