After the death of Brittany Murphy, Silverstone stated that she "always felt connected to [Murphy] as [they] shared a very special experience in [their] lives together." Following Murphy's death, Silverstone reported in an interview: "I loved working with Brittany. She was so talented, so warm, and so sweet."
Heckerling later described Silverstone as having "that Marilyn Monroe thing" as a "pretty, sweet blonde who, in spite of being the American ideal, people still really like."
The cast reunited in 2012 for an issue of Entertainment Weekly.
Heckerling later reunited with both Silverstone and Shawn for the vampire comedy Vamps.
Clueless is the main inspiration for Australian rapper Iggy Azalea's music video to her U.S. number one hit single "Fancy" featuring Charli XCX, with many visuals as well as costumes inspired by the film. The video is filled with remakes of classic Clueless scenes, and the outfits are reinvented to channel the famous stylings of the film with a slightly modern edge. "Fancy" was also shot in the same Los Angeles high school where Clueless was filmed.
In 2015, to celebrate the film's twentieth anniversary, pop culture writer Jen Chaney published a book titled As If!: The Oral History of Clueless, based on exclusive interviews with writer/director Amy Heckerling, star Alicia Silverstone, and other cast and crew members. Excerpts from the book were published in Vanity Fair magazine.