The play is set in a few small locales—a hospital room, a studio, a pair of living rooms, a café, a room in the museum, in front of a photo at a showing, a doctor's office, a bench in front of a suggested aquarium. The text of the play insists on all settings being "minimal". Though evocative of real happenings, the lack of physical detail in setting is meant to balance the verbal excess. Places are evoked, not shown—benches instead of the front of a museum; a large photo instead of the entire showing.
According to Robert Brustein, in the original production, "Memorial blocks constitute the backdrop of the set—a design that gradually accumulates all the scenic pieces used in the play, as if these four lives were a detritus of props and furniture." The setting is formed to be deliberately symbolic.