Call of the Wild

how dose the setting influences a major conflict between the to major characters because

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The setting of London's stories take place in the wildness of the Canadian landscape. Everything about the harsh uncompromising wilderness affects every character in the novel. The wilderness itself is a character as it freezes and tests each character to the limit. For Buck, the protagonist, the wilderness is his calling. The wildness defines him. The humans all navigate the harsh conditions with the help of their dogs and their own ingenuity. They must know when to respect the boundaries that nature dictates.