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Adaptations and cultural references

Selected stage productions

• 1931, John Gielgud as Antony and Ralph Richardson as Enobarbus at the Old Vic Theatre.
• 1947, Katharine Cornell won a Tony Award for her Broadway performance of Cleopatra opposite the Antony of Godfrey Tearle. It ran for 126 performances, the longest run of the play in Broadway history.
• 1951, Laurence Olivier as Antony and Vivien Leigh as Cleopatra in a production that played in repertory with George Bernard Shaw's Caesar and Cleopatra at the St James's Theatre and later on Broadway.
• 1953, Michael Redgrave played Antony and Peggy Ashcroft played Cleopatra at the Shakespeare Memorial Theatre.
• 1972, Janet Suzman and Richard Johnson in Trevor Nunn's production for the Royal Shakespeare Company
• 1981, Timothy Dalton played Antony and Carmen Du Sautoy played Cleopatra at the Mermaid Theatre.
• 1986, Timothy Dalton and Vanessa Redgrave in the title roles at Clwyd Theatr Cymru and Haymarket Theatre.
• 1999, Alan Bates and Frances de la Tour in title roles, Guy Henry as Octavius (also David Oyelowo and Owen Oakeshott) at the Royal Shakespeare Company.
• 1999, Paul Shelley as Antony and Mark Rylance as Cleopatra in an all male cast production at Shakespeare's Globe Theatre in London.
• 2006, Patrick Stewart and Harriet Walter in the title roles at the Royal Shakespeare Company.
• 2010, Kim Cattrall and Jeffery Kissoon in the title roles at the Liverpool Playhouse.
• 2010, Kate Mulgrew and John Douglas Thompson in a production directed by Tina Landau at Hartford Stage.
• 2010, Kathryn Hunter and Darrell D'Silva in the title roles at the Royal Shakespeare Company.

Films and TV

• Antony and Cleopatra, 1908
• Antony and Cleopatra, 1972, directed by and starring Charlton Heston as Antony, Hildegarde Neil as Cleopatra and also featuring Eric Porter as Enobarbus.
• Antony & Cleopatra, 1974, a television production of Trevor Nunn's stage version performed by London's Royal Shakespeare Company. This version was shown in the United States to great acclaim in 1975. It stars Janet Suzman (Cleopatra), Richard Johnson (Antony), and Patrick Stewart (Enobarbus).
• Antony & Cleopatra, 1981, a TV production made as part of the BBC Television Shakespeare series. It stars Colin Blakely (Antony), Jane Lapotaire (Cleopatra), and Ian Charleson (Octavius).
• Antony and Cleopatra, a 1983 TV movie. It stars Timothy Dalton (Antony) and Lynn Redgrave (Cleopatra).
• Rome, TV Series 2005-2007, featured James Purefoy and Lyndsey Marshal as Antony and Cleopatra.

Musical adaptations

• Samuel Barber's operatic version of the play was premièred in 1966.

Brahms 4th symphony is inspired by the play.